Stem Cell Implant New Discovery

Even though I mentioned that the stem cell therapy using olfactory mucosa is the cure with most potential, it still had some issues such as formations of tumors after stem cell implantations. However at the beginning of April this year, the researchers from journal Frontiers in Cellular Neuroscience published that stem cell implants along with an anti-cancer drug has been proven to be effective against Parkinson’s disease symptoms in mice reported by NDTV.com. Scientists used two groups of mice, one treated with the stem cell therapy without anti-cancer medication also used as a control group and another group treated with stem cell therapy with anti-cancer drug to detect this new finding. This finding is extremely important because the researchers used FDA approved anti cancer drug along with the stem cell therapy and after the cell implantation, there were no tumors formed in mice. The cells were induced to differentiate into dopamine (neurotransmitters that act as signals between our brain and body and crucial for physical movements)-producing cells and maintained healthy and functional state even after 15 months later. Furthermore, the researchers discovered that cells from the stem cell therapy with anti-cancer drugs released more dopamines, compare to regular stem cells from control group mice. Also another reason why this result is significant because developments of stem cell therapy leads to not only a cure for Parkinson’s disease but also for other progressive brain diseases such as Alzheimer’s disease and Lou Gehrig’s disease also known as ALS. Currently for Parkinson’s disease, researches with mice have been conducted to figure out a way for the stem cell therapy. With these discoveries, scholars and researchers in biology field can develop even further with the cure and human trials could be possible. Even though there are many barriers to overcome with stem cell therapy, if scholars and researchers continue to make these kinds of progressive steps, this potential cure could be available to patients even sooner.

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Parkinson's disease and Olfactory Mucosa

This blog was created to inform people about Parkinson’s disease and a possible future cure for the disease. Parkinson’s disease is a progressive and chronic disease, which restricts body movements by causing disorders in the central nervous system. Disorders in the central nervous system cause deaths of the neurons, cells that produce dopamines in the brain and directly linked to physical movements. This deadly disease is one of the most common diseases that affects about 1 million people in North America.

Currently, there are several medications available and the most effective one is called Sinemet. However, this medication causes many side effects to the patients such as nausea and vomiting and it becomes ineffective over the time. There is no cure is available for Parkinson’s disease and since Parkinson’s disease is a progressive disease, the accessible treatments and medications can only slow down acceleration of the disease and it cannot be eradicated. Parkinson’s disease can be cured through stem cell therapies, using stem cells to replace dead neurons and produce dopamines in the brain. However, the present science and technologies are very limited and there is no accessible source for the therapy.

However, many scholars and scientists recently discovered a tissue located in the nasal cavity called olfactory mucosa, which could be a potential source for stem cells. According to numerous literature reviews and research papers, some researchers successfully extracted olfactory mucosa from human body and managed to differentiate the tissue into a neuron producing tissue by injecting it into several mice. The researches are still going on to prove olfactory mucosa as a stem cell source and if olfactory mucosa can be differentiated into human neuron cells, many people suffering from Parkinson’s disease can be free from physical restrictions. Furthermore, it can hasten the discoveries of cures for other chronic diseases too.