Monday, May 11, 2015

Olfactory mucosa used as a treatment for spinal cord injury

I was trying to look for a peer-reviewed article regarding Parkinson’s disease and usage of olfactory mucosa stem cell therapy but I couldn’t find any article from past three years. Another article I found is about using olfactory ensheathing cells (OEC) as a stem cell source for spinal cord repair. Like Parkinson’s disease, spinal cord injury has no cure available for patients. It is a permanent disability and it is impossible restore functions with current medical treatments. Based on information from this article, researchers discovered potential from OEC to cure this incurable disability. Researchers prepared five different groups of rodent and their backs were paralyzed by anesthesia in order to create similar situation as spinal cord injuries. Then they were treated with OED transplantation except the control group and experimenters record Cord Dorsum Potential (CDP), which shows the potential of spinal cord movement. By conducting OED transplantation to treat spinal cord injury, researchers were trying to test the safety and efficacy of OED transplantation. The result showed that all rodent groups treated with OED transplantation showed a significant improvement on CDP compared to the CDP of control group. The results did not only exhibit a massive improvement on the potential of spinal cord movement, but also proved that OED definitely has a chance to become a cure for the injury. Many people might think these results as negligible and useless because it is performed on rodents but from my perspective, conducting these experiments seem essential in order to develop the ultimate cure in the end. It is true that the results from animal based experiment are usually very different from human trials however, with continuous attempts on using OED as a cure will eventually lead to another discoveries and also will cause other people to more aware about olfactory mucosa.


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